Routine Vaccines to Reduce Dementia?
Discussion
An interesting research study with the usual caveat 'more research is needed' buy I'm surprised it hasn't gained greater awareness. Whilst these vaccines are free on the NHS for the over 65 (or vulnerable) if you're not eligible the Shingles vaccine is near £500 on it's own!
I'm questioning whether to wait until 65 or take some preventative measures now? Has anyone studied this in depth and taken action?
[i]Recent large-scale observational studies show that routine adult vaccines are associated with a 25% to 55% reduction in the risk of developing dementia or Alzheimer's disease.
Key Vaccines Linked to Lower Dementia Risk:
- Shingles (Herpes Zoster): Associated with a 20% to 40% lower risk of dementia. Newer recombinant options like Shingrix show particularly strong potential in extending dementia-free time. ( Harvard health recommend this for adults 50 and over!)
- Influenza (Flu): Regular annual flu vaccination is linked to up to a 40% lower risk of Alzheimer's, with high-dose formulations showing potential risk reductions of up to 55% in recent preliminary studies.
- RSV (Respiratory Syncytial Virus): Newer RSV vaccines (such as Arexvy) have been linked to a 29% reduction in dementia risk over an 18-month window, potentially aided by shared immune adjuvants.
- Tdap/Td (Tetanus, Diphtheria, Pertussis): Associated with a roughly 30% reduction in developing Alzheimer's or general dementia over long-term follow-ups.
- Pneumococcal: Linked to a 27% lower risk of Alzheimer's disease and broader cognitive protection.[/i]
I'm questioning whether to wait until 65 or take some preventative measures now? Has anyone studied this in depth and taken action?
[i]Recent large-scale observational studies show that routine adult vaccines are associated with a 25% to 55% reduction in the risk of developing dementia or Alzheimer's disease.
Key Vaccines Linked to Lower Dementia Risk:
- Shingles (Herpes Zoster): Associated with a 20% to 40% lower risk of dementia. Newer recombinant options like Shingrix show particularly strong potential in extending dementia-free time. ( Harvard health recommend this for adults 50 and over!)
- Influenza (Flu): Regular annual flu vaccination is linked to up to a 40% lower risk of Alzheimer's, with high-dose formulations showing potential risk reductions of up to 55% in recent preliminary studies.
- RSV (Respiratory Syncytial Virus): Newer RSV vaccines (such as Arexvy) have been linked to a 29% reduction in dementia risk over an 18-month window, potentially aided by shared immune adjuvants.
- Tdap/Td (Tetanus, Diphtheria, Pertussis): Associated with a roughly 30% reduction in developing Alzheimer's or general dementia over long-term follow-ups.
- Pneumococcal: Linked to a 27% lower risk of Alzheimer's disease and broader cognitive protection.[/i]
Hoofy said:
Weird. Any thoughts why these vaccines are linked to this? Or is it a case of causation vs correlation?
No idea, it's part of a study of 1M+ people I'm led to believe. Sky News apparently reported on it earlier this year but the conclusion was 'more research is needed'.You would think if it had traction the NHS would be behind it and offer the vaccines free for those under 65, the positive benefits as reported would reduce the impact on social care etc down the line?
Armitage.Shanks said:
Key Vaccines Linked to Lower Dementia Risk:
- Shingles (Herpes Zoster): Associated with a 20% to 40% lower risk of dementia. Newer recombinant options like Shingrix show particularly strong potential in extending dementia-free time. ( Harvard health recommend this for adults 50 and over!)
- Influenza (Flu): Regular annual flu vaccination is linked to up to a 40% lower risk of Alzheimer's, with high-dose formulations showing potential risk reductions of up to 55% in recent preliminary studies.
- RSV (Respiratory Syncytial Virus): Newer RSV vaccines (such as Arexvy) have been linked to a 29% reduction in dementia risk over an 18-month window, potentially aided by shared immune adjuvants.
- Tdap/Td (Tetanus, Diphtheria, Pertussis): Associated with a roughly 30% reduction in developing Alzheimer's or general dementia over long-term follow-ups.
- Pneumococcal: Linked to a 27% lower risk of Alzheimer's disease and broader cognitive protection.[/i]
Of those 5 jabs , my MIL and FIL had all of them except the RSV.- Shingles (Herpes Zoster): Associated with a 20% to 40% lower risk of dementia. Newer recombinant options like Shingrix show particularly strong potential in extending dementia-free time. ( Harvard health recommend this for adults 50 and over!)
- Influenza (Flu): Regular annual flu vaccination is linked to up to a 40% lower risk of Alzheimer's, with high-dose formulations showing potential risk reductions of up to 55% in recent preliminary studies.
- RSV (Respiratory Syncytial Virus): Newer RSV vaccines (such as Arexvy) have been linked to a 29% reduction in dementia risk over an 18-month window, potentially aided by shared immune adjuvants.
- Tdap/Td (Tetanus, Diphtheria, Pertussis): Associated with a roughly 30% reduction in developing Alzheimer's or general dementia over long-term follow-ups.
- Pneumococcal: Linked to a 27% lower risk of Alzheimer's disease and broader cognitive protection.[/i]
MIL developed Alzheimer’s in her 80’s , and died after a fall aged 92. FIL still going strong including driving at 93.
My Mother only had the Flu jab ( doesn’t everyone get a tetanus as a child or subsequently ?) and was doing fine until last year when at 84 early onset Alzheimer’s first diagnosed.
My Father only had the flu jab but died at 74 after a heart attack.
Not sure therefore how this all translates ?!
Armitage.Shanks said:
Hoofy said:
Weird. Any thoughts why these vaccines are linked to this? Or is it a case of causation vs correlation?
No idea, it's part of a study of 1M+ people I'm led to believe. Sky News apparently reported on it earlier this year but the conclusion was 'more research is needed'.You would think if it had traction the NHS would be behind it and offer the vaccines free for those under 65, the positive benefits as reported would reduce the impact on social care etc down the line?
alscar said:
Armitage.Shanks said:
Key Vaccines Linked to Lower Dementia Risk:
- Shingles (Herpes Zoster): Associated with a 20% to 40% lower risk of dementia. Newer recombinant options like Shingrix show particularly strong potential in extending dementia-free time. ( Harvard health recommend this for adults 50 and over!)
- Influenza (Flu): Regular annual flu vaccination is linked to up to a 40% lower risk of Alzheimer's, with high-dose formulations showing potential risk reductions of up to 55% in recent preliminary studies.
- RSV (Respiratory Syncytial Virus): Newer RSV vaccines (such as Arexvy) have been linked to a 29% reduction in dementia risk over an 18-month window, potentially aided by shared immune adjuvants.
- Tdap/Td (Tetanus, Diphtheria, Pertussis): Associated with a roughly 30% reduction in developing Alzheimer's or general dementia over long-term follow-ups.
- Pneumococcal: Linked to a 27% lower risk of Alzheimer's disease and broader cognitive protection.[/i]
Of those 5 jabs , my MIL and FIL had all of them except the RSV.- Shingles (Herpes Zoster): Associated with a 20% to 40% lower risk of dementia. Newer recombinant options like Shingrix show particularly strong potential in extending dementia-free time. ( Harvard health recommend this for adults 50 and over!)
- Influenza (Flu): Regular annual flu vaccination is linked to up to a 40% lower risk of Alzheimer's, with high-dose formulations showing potential risk reductions of up to 55% in recent preliminary studies.
- RSV (Respiratory Syncytial Virus): Newer RSV vaccines (such as Arexvy) have been linked to a 29% reduction in dementia risk over an 18-month window, potentially aided by shared immune adjuvants.
- Tdap/Td (Tetanus, Diphtheria, Pertussis): Associated with a roughly 30% reduction in developing Alzheimer's or general dementia over long-term follow-ups.
- Pneumococcal: Linked to a 27% lower risk of Alzheimer's disease and broader cognitive protection.[/i]
MIL developed Alzheimer s in her 80 s , and died after a fall aged 92. FIL still going strong including driving at 93.
My Mother only had the Flu jab ( doesn t everyone get a tetanus as a child or subsequently ?) and was doing fine until last year when at 84 early onset Alzheimer s first diagnosed.
My Father only had the flu jab but died at 74 after a heart attack.
Not sure therefore how this all translates ?!
Interesting reading. It's something which I find fascinating, but personally follows longevity expert Dr. Peter Attia, who states that exercise is the single most powerful tool we have to prevent Alzheimer’s and dementia. It far outperforms any drug, supplement, or cognitive puzzle. His book, Outlived, is well worth a read.
Hoofy said:
Guess it's about percentage risk, so taking a massive number of people and seeing what the chances are.
Indeed , I meant that for the four people I mentioned the results would be very non conclusive so as you say would need a massive amount more number of cases to prove either way. Bill said:
Hoofy said:
Weird. Any thoughts why these vaccines are linked to this? Or is it a case of causation vs correlation?
It's possible illness makes dementia more likely so preventing illness helps.Preventing illness has got to be the way, and keeping fit.
My mum got a UTI and fainted. Broke her shoulder and cocyxx thus spent about 5 to 6 weeks in hospital. She's 86 and has gone from independent to having carers and us 3 sons taking turns to stay with her now she's home.
A little inconvenient as she doesn't live in the UK.
Her rapid mental decline is a little worrying.
My mum got a UTI and fainted. Broke her shoulder and cocyxx thus spent about 5 to 6 weeks in hospital. She's 86 and has gone from independent to having carers and us 3 sons taking turns to stay with her now she's home.
A little inconvenient as she doesn't live in the UK.
Her rapid mental decline is a little worrying.
croyde said:
Preventing illness has got to be the way, and keeping fit.
My mum got a UTI and fainted. Broke her shoulder and cocyxx thus spent about 5 to 6 weeks in hospital. She's 86 and has gone from independent to having carers and us 3 sons taking turns to stay with her now she's home.
A little inconvenient as she doesn't live in the UK.
Her rapid mental decline is a little worrying.
Yikes. Sorry to hear that.My mum got a UTI and fainted. Broke her shoulder and cocyxx thus spent about 5 to 6 weeks in hospital. She's 86 and has gone from independent to having carers and us 3 sons taking turns to stay with her now she's home.
A little inconvenient as she doesn't live in the UK.
Her rapid mental decline is a little worrying.
croyde said:
Preventing illness has got to be the way, and keeping fit.
My mum got a UTI and fainted. Broke her shoulder and cocyxx thus spent about 5 to 6 weeks in hospital. She's 86 and has gone from independent to having carers and us 3 sons taking turns to stay with her now she's home.
A little inconvenient as she doesn't live in the UK.
Her rapid mental decline is a little worrying.
Sorry to hear that. My mum got a UTI and fainted. Broke her shoulder and cocyxx thus spent about 5 to 6 weeks in hospital. She's 86 and has gone from independent to having carers and us 3 sons taking turns to stay with her now she's home.
A little inconvenient as she doesn't live in the UK.
Her rapid mental decline is a little worrying.
Unfortunately it is pretty common with those over a certain age and why many say that trying to prevent the fall in the first place is best which of course is a lot easier said than done.
My MIL had Alzheimer’s but was coping at home with the help of her husband as carer when she too had a fall and went into hospital from where she sadly didn’t emerge.
S100HP said:
Interesting reading. It's something which I find fascinating, but personally follows longevity expert Dr. Peter Attia, who states that exercise is the single most powerful tool we have to prevent Alzheimer s and dementia. It far outperforms any drug, supplement, or cognitive puzzle. His book, Outlived, is well worth a read.
This is correct - as a relatively simple intervention it has the single greatest effect size. Exercise also boosts the immune system and helps it fight infections. The is also likely related to reducing the harmful effects of inflammation.Wonder about the direction of causality with a study like this.
Those who take up all offers of vaccination are likely to be the most motivated, best informed, socially connected and independent. Vice versa for those missing vaccines. Those taking up vaccination have protective factors; those missing may already be in the foothills of dementia.
Those who take up all offers of vaccination are likely to be the most motivated, best informed, socially connected and independent. Vice versa for those missing vaccines. Those taking up vaccination have protective factors; those missing may already be in the foothills of dementia.
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