Antibiotics and Alcohol
Discussion
There is no chemical interaction whatsoever between alcohol and Penicillin based antibiotics.
However, with other antibiotics, alcohol reduces the absorption of doxycycline and tetracycline and interacts quite nastily with metronidazole and tinidazole (potentially causing abdominal pain, nausea, vomiting and tachycardia)
However, with other antibiotics, alcohol reduces the absorption of doxycycline and tetracycline and interacts quite nastily with metronidazole and tinidazole (potentially causing abdominal pain, nausea, vomiting and tachycardia)
Edited by maddog993 on Friday 5th June 18:24
(just the one!)When I was much younger docs ALWAYS told us never to drink any alcohol with antibiotics, but as the years have passed they seem to have stop saying it.
Apparently the booze just generally causes your body to heal slower, and/or washes the antibiotics out of the system.
So if you're ill, and want to get better, keep your body in the best condition you can, with food, sleep, booze, exercise all taken in moderation.
Apparently the booze just generally causes your body to heal slower, and/or washes the antibiotics out of the system.
So if you're ill, and want to get better, keep your body in the best condition you can, with food, sleep, booze, exercise all taken in moderation.
King Herald said:
Apparently the booze just generally causes your body to heal slower, and/or washes the antibiotics out of the system.
I'd always thought the diuretic effect of alcohol was a big factor.Personally I can't really see why you'd want to go boozing when you feel bad enough to require medication.
King Herald said:
When I was much younger docs ALWAYS told us never to drink any alcohol with antibiotics, but as the years have passed they seem to have stop saying it.
Apparently the booze just generally causes your body to heal slower, and/or washes the antibiotics out of the system.
While you're right in stating excess alcohol impairs healing processes in the body - it won't wash antibiotics out of the system.Apparently the booze just generally causes your body to heal slower, and/or washes the antibiotics out of the system.
The myth regarding not consuming alcohol with penicillin arose through the treatment of STDs in the original VD clinics; It was felt that the promiscuous behaviour 'fuelled' by alcohol would lead to STD sufferers transmitting their disease to others before the penicillin had cleared it up and patients were thus told not to consume alcohol while taking the penicillin. The propensity of Docs to give this advice carried on through the years in many cases despite it being known that there is no significant interaction between penicillin and alcohol.
BigAlinEmbra said:
I'd always thought the diuretic effect of alcohol was a big factor.
If anything, theoretically the diuretic action of alcohol would actually prolong the action of penicillin through inhibiting it's excretion via the epithelium of the renal capillaries.Edited by maddog993 on Saturday 6th June 18:25
maddog993 said:
While you're right in stating excess alcohol impairs healing processes in the body - it won't wash antibiotics out of the system.
The myth regarding not consuming alcohol with penicillin arose through the treatment of STDs in the original VD clinics; It was felt that the promiscuous behaviour 'fuelled' by alcohol would lead to STD sufferers transmitting their disease to others before the penicillin had cleared it up and patients were thus told not to consume alcohol while taking the penicillin. The propensity of Docs to give this advice carried on through the years in many cases despite it being known that there is no significant interaction between penicillin and alcohol.
Is that right? That's very interesting! The myth regarding not consuming alcohol with penicillin arose through the treatment of STDs in the original VD clinics; It was felt that the promiscuous behaviour 'fuelled' by alcohol would lead to STD sufferers transmitting their disease to others before the penicillin had cleared it up and patients were thus told not to consume alcohol while taking the penicillin. The propensity of Docs to give this advice carried on through the years in many cases despite it being known that there is no significant interaction between penicillin and alcohol.
Edited by maddog993 on Saturday 6th June 18:25
BigAlinEmbra said:
King Herald said:
Apparently the booze just generally causes your body to heal slower, and/or washes the antibiotics out of the system.
I'd always thought the diuretic effect of alcohol was a big factor.Personally I can't really see why you'd want to go boozing when you feel bad enough to require medication.
Its been 10 days now since I've felt human
maddog993 said:
BigAlinEmbra said:
I'd always thought the diuretic effect of alcohol was a big factor.
If anything, theoretically the diuretic action of alcohol would actually prolong the action of penicillin through inhibiting it's excretion via the epithelium of the renal capillaries.Edited by maddog993 on Saturday 6th June 18:25
(Mr Mackey impression over)
It really makes more sense to not mix your medication and your booze.
All these arguments about diuretics and increasing the effect. If you take a diuretic and the antibiotic is excreted renally. Does that not mean that the diuretic increases the excretion of the antibiotic, rendering it less effective?
All these arguments about diuretics and increasing the effect. If you take a diuretic and the antibiotic is excreted renally. Does that not mean that the diuretic increases the excretion of the antibiotic, rendering it less effective?
The diuretic effect of alcohol is based on it's inhibition of the anti-diuretic hormone(ADH) Vasopressin;
Studies on the effects of diuretics (including ADH inhibitors) have actually shown that-despite what you might expect- the excretion of Penicillin is significantly reduced by the use of diuretics (to the extent that Frusemide - a very potent loop diuretic- is actually superior in this respect to Ethamide which is specifically used to retain penicillin within the system and prolong it's action)
Studies on the effects of diuretics (including ADH inhibitors) have actually shown that-despite what you might expect- the excretion of Penicillin is significantly reduced by the use of diuretics (to the extent that Frusemide - a very potent loop diuretic- is actually superior in this respect to Ethamide which is specifically used to retain penicillin within the system and prolong it's action)
Edited by maddog993 on Sunday 7th June 18:26
maddog993 said:
The diuretic effect of alcohol is based on it's inhibition of the anti-diuretic hormone(ADH) Vasopressin;
Studies on the effects of diuretics (including ADH inhibitors) have actually shown that-despite what you might expect- the excretion of Penicillin is significantly reduced by the use of diuretics (to the extent that Frusemide - a very potent loop diuretic- is actually superior in this respect to Ethamide which is specifically used to retain penicillin within the system and prolong it's action)
I seem to recall hearing something along the lines that that early penicillin taking patients used to have to drink their own pee, because the drug passed through them so quickly and they could never produce enough to keep up with demand. Boer war maybe, or was it after that? Studies on the effects of diuretics (including ADH inhibitors) have actually shown that-despite what you might expect- the excretion of Penicillin is significantly reduced by the use of diuretics (to the extent that Frusemide - a very potent loop diuretic- is actually superior in this respect to Ethamide which is specifically used to retain penicillin within the system and prolong it's action)
Driller said:
Drinking alcohol with the antibiotic metronidazole can cause a Disulfuram-like reaction ie severe vomting.
I've just been having a "discussion" with someone about an alcholic being prescribed Metronidazole for dental pain, someone popped up and said only 10% of people will suffer severe vomiting if they mixed. Still not something I'd think was appropriate!
Rach* said:
Driller said:
Drinking alcohol with the antibiotic metronidazole can cause a Disulfuram-like reaction ie severe vomting.
I've just been having a "discussion" with someone about an alcholic being prescribed Metronidazole for dental pain, someone popped up and said only 10% of people will suffer severe vomiting if they mixed. Still not something I'd think was appropriate!
as long as it does not mention potentiate with it, should be ok - some rep gave my gp some great new hayfever pills, me and some patients got to try them, went camping on the weekend and had a fair bit of booze, the pills had the effect of trippling the effect of what was drunk. this was several years ago, came back and told the GP that wanted off them, he asked did I rape someone ?
seems one of the other patients did rape someone and can understand how easy it must have been to slip over
seems one of the other patients did rape someone and can understand how easy it must have been to slip over
Driller said:
Rach* said:
Driller said:
Drinking alcohol with the antibiotic metronidazole can cause a Disulfuram-like reaction ie severe vomting.
I've just been having a "discussion" with someone about an alcholic being prescribed Metronidazole for dental pain, someone popped up and said only 10% of people will suffer severe vomiting if they mixed. Still not something I'd think was appropriate!
Rach* said:
Driller said:
Rach* said:
Driller said:
Drinking alcohol with the antibiotic metronidazole can cause a Disulfuram-like reaction ie severe vomting.
I've just been having a "discussion" with someone about an alcholic being prescribed Metronidazole for dental pain, someone popped up and said only 10% of people will suffer severe vomiting if they mixed. Still not something I'd think was appropriate!
What do you tell your Perio patients when they have it prescribed?
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