High dose methotrexate for ALL Cancer
Discussion
Hi everyone sorry for being a pain. I would just like to know if anyone knows what the side effects of 120mg of Methotrexate within 24 hours will do to a 10 year old child. His Neutraphil count is 1.30 will this make him netrapenic with in a few days? And what are the other side effects. I have been given a regime of what I need to give him in the next 24 hours and then folinic acid after 48 hours after the 1st dose. Is there anything I should look out for? He has had VRE and have been told he is on isolation for the rest of the treatment (2.5 years) I Know the complications with this! Whoops sorry he has testicular relapse of Acute lymphoblastic luekemia cancer. He has had the intesive treatment which they could not finish due to the hospital resistant bug VRE and recently had 3 weeks of everyday radiotherapy.
Doctors are not that receptive to questions!!!!!
So I would be greatful if any of you know. We would so love to go out over the bank holiday but don't want to if he becomes netrapenic and will pick up a bug in 2 seconds flat! We know if he gets a bug it will spure off the VRE and could kill him so we have to be careful. Are we house bound again!!???
Thank you everyone XXXXXXXXXXXXXXXXXXXXXxxx
Doctors are not that receptive to questions!!!!!
So I would be greatful if any of you know. We would so love to go out over the bank holiday but don't want to if he becomes netrapenic and will pick up a bug in 2 seconds flat! We know if he gets a bug it will spure off the VRE and could kill him so we have to be careful. Are we house bound again!!???
Thank you everyone XXXXXXXXXXXXXXXXXXXXXxxx
space1999 said:
Hi everyone sorry for being a pain. I would just like to know if anyone knows what the side effects of 120mg of Methotrexate within 24 hours will do to a 10 year old child. His Neutraphil count is 1.30 will this make him netrapenic with in a few days? And what are the other side effects. I have been given a regime of what I need to give him in the next 24 hours and then folinic acid after 48 hours after the 1st dose. Is there anything I should look out for? He has had VRE and have been told he is on isolation for the rest of the treatment (2.5 years) I Know the complications with this! Whoops sorry he has testicular relapse of Acute lymphoblastic luekemia cancer. He has had the intesive treatment which they could not finish due to the hospital resistant bug VRE and recently had 3 weeks of everyday radiotherapy.
Doctors are not that receptive to questions!!!!!
So I would be greatful if any of you know. We would so love to go out over the bank holiday but don't want to if he becomes netrapenic and will pick up a bug in 2 seconds flat! We know if he gets a bug it will spure off the VRE and could kill him so we have to be careful. Are we house bound again!!???
Thank you everyone XXXXXXXXXXXXXXXXXXXXXxxx
Are you being serious?Doctors are not that receptive to questions!!!!!
So I would be greatful if any of you know. We would so love to go out over the bank holiday but don't want to if he becomes netrapenic and will pick up a bug in 2 seconds flat! We know if he gets a bug it will spure off the VRE and could kill him so we have to be careful. Are we house bound again!!???
Thank you everyone XXXXXXXXXXXXXXXXXXXXXxxx
Uhura_Fighter said:
Would you be best speaking to your/a doctor? (This is pistonheads)
Good luck with everything and hope you get a good weekend whatever.
I tried and they avoided the question 3 times!!!!!! Good luck with everything and hope you get a good weekend whatever.
And thank you our family needs a good weekend away after 3 months in hospital and 3 weeks in intesive care! So we are desperate to know.
AND sorry you PH'ers are just brill on these subjects sometimes! Specially when doctors avoid questions!!! So yes this is Piston heads and arn't you all fab! X
Lagerlout said:
Sorry to hear of your situation, sounds like a nightmare but best of luck to you and yours. Have you tried asking questions on the Macmillan Cancer forum? Might be the best place to ask?
Thank you for that site and it did help a little but he has had methotrexate every week (every friday) part of his maintence chemo and lubar puncture meths but is now on an 8 week cycle due to the start of another cycle for relapse and has not had this part before. I have checked the internet for help but it won't tell you about the high dose oral meths along with the high dose Mercaptopurine (6mp). He stayed in hospital for the one through his wiggley (sorry central line) but this is another stage again. It did help and I appreciate it alot XCopied over from the lounge.
Frankly with a neutrophil count of under 2, I wouldn't take him anywhere he could get a bug anyway.
I'm no doctor and I was never given methotrexate myself as a patient, but I imagine it will knock his neutrophils somehow. I've just had a read of the BNF and it mentions that neutropenia is a less common side effect, but still possible.
I wouldn't risk it. A day out isn't worth him catching an infection that he isn't very well equipped to fight.
Surely you can ring the unit that are looking after your little 'un? Getting unqualified advice with such a serious thing is madness. I know my Doc's were extremely receptive to questions and someone was available 24hrs a day. You might not like their answers, but I'd be very surprised if they tried to put you off gleaning any information, that would be extremely unprofessional.
I imagine the Doc's will default to NO in this case though. I would if I was them. I know how dodgy it was when I was neutropenic and how easy it was to pick up a minor bug. Having seen 4 people I knew die on the ward thanks to infections picked up whilst neutropenic, I'd say don't do it.
Frankly with a neutrophil count of under 2, I wouldn't take him anywhere he could get a bug anyway.
I'm no doctor and I was never given methotrexate myself as a patient, but I imagine it will knock his neutrophils somehow. I've just had a read of the BNF and it mentions that neutropenia is a less common side effect, but still possible.
I wouldn't risk it. A day out isn't worth him catching an infection that he isn't very well equipped to fight.
Surely you can ring the unit that are looking after your little 'un? Getting unqualified advice with such a serious thing is madness. I know my Doc's were extremely receptive to questions and someone was available 24hrs a day. You might not like their answers, but I'd be very surprised if they tried to put you off gleaning any information, that would be extremely unprofessional.
I imagine the Doc's will default to NO in this case though. I would if I was them. I know how dodgy it was when I was neutropenic and how easy it was to pick up a minor bug. Having seen 4 people I knew die on the ward thanks to infections picked up whilst neutropenic, I'd say don't do it.
OK I used to be a race mechanic, and now manage a warehouse clearly I have no idea about anything this important.
I just wanted to wish you all the best really, as someone else here said speak to a charity or your Doctor and if you feel inclined, maybe a post about raising money with Pistonheads members for Cancer or Leukemia would be a better bet.
I'm sure you'd raise a lot, the majority of members here seem to be decent people!
I just wanted to wish you all the best really, as someone else here said speak to a charity or your Doctor and if you feel inclined, maybe a post about raising money with Pistonheads members for Cancer or Leukemia would be a better bet.
I'm sure you'd raise a lot, the majority of members here seem to be decent people!
Edited by Snoop Bagg on Friday 22 May 12:56
OK I used to be a race mechanic, and now manage a warehouse clearly I have no idea about anything this important.
I just wanted to wish you all the best really, as someone else here said speak to a charity or your Doctor and if you feel inclined, maybe a post about raising money with Pistonheads members for Cancer or Leukemia else would be a better bet.
I'm sure you'd raise a lot, the majority of members here seem to be very decent people!
I just wanted to wish you all the best really, as someone else here said speak to a charity or your Doctor and if you feel inclined, maybe a post about raising money with Pistonheads members for Cancer or Leukemia else would be a better bet.
I'm sure you'd raise a lot, the majority of members here seem to be very decent people!
Edited by Snoop Bagg on Friday 22 May 13:26
....er they really should answer your specific queries.It's a wacking dose and would probably make an elephant neutropenic so best keep out of harm's way as suggested above. This does not constitute specific medical advice yadda yadda etc.
..Sorry can't get over their aversion to answering your questions.
..Sorry can't get over their aversion to answering your questions.
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