High levels of cod liver oil/fish oil
Discussion
Good to know, was wondering if there might be unseen/unfelt effects that might present themselves at a later time. I'm doing this because, just in case anyone else is interested, fish oil/CLO is apparently good at binding to LDL/cholesterol and eliminating it, helping to prevent arterial wall thickening.
ReverendCounter said:
I currently take 1.2g of fish oil capsules (12x1000mg) over the course of the day. Is this going to cause any long term unwanted effects?
I'm sure you tried google but in summary, 1g a day is unlikely to cause major side effects, but may have a small effect on blood clotting.https://www.healthline.com/nutrition/fish-oil-side...
ReverendCounter said:
Good to know, was wondering if there might be unseen/unfelt effects that might present themselves at a later time. I'm doing this because, just in case anyone else is interested, fish oil/CLO is apparently good at binding to LDL/cholesterol and eliminating it, helping to prevent arterial wall thickening.
Dr Rhonda Patrick has lots of good things to say on the research.Evanivitch said:
I'm sure you tried google but in summary, 1g a day is unlikely to cause major side effects, but may have a small effect on blood clotting.
https://www.healthline.com/nutrition/fish-oil-side...
Thanks for the link, I hadn't googled yet, just basically ramped up from one a day to the current levels over the last year or so.https://www.healthline.com/nutrition/fish-oil-side...
Incidentally this doc in the US claims 'he reversed 20 years of arterial plaque' which I didn't think was practically possible but he goes into some detail about his own health, the process and the results.
https://prevmedhealth.com/how-to-reverse-arterial-...
Basically boils down to taking higher levels of Omega 3, adding higher levels of niacin to the diet than the RDA, statins, and for his own personal circumstances, a blood pressure medication (ACE inhibitor, ramipril).
https://prevmedhealth.com/how-to-reverse-arterial-...
Basically boils down to taking higher levels of Omega 3, adding higher levels of niacin to the diet than the RDA, statins, and for his own personal circumstances, a blood pressure medication (ACE inhibitor, ramipril).
Interesting, because after a heart attack 10 years ago, amongst the recommended daily medication to reduce the risk of another attack was Fish Oil capsules. However, a clinical decision was made some years later that there was not enough evidence to support the claims, therefore Fish Oil was removed from the recommended medication. It was preferable for patients to simply include oily fish as part of a healthy diet. I guess if you take capsules your body will use what it needs and get rid of the rest.
bigpriest said:
Interesting, because after a heart attack 10 years ago, amongst the recommended daily medication to reduce the risk of another attack was Fish Oil capsules. However, a clinical decision was made some years later that there was not enough evidence to support the claims, therefore Fish Oil was removed from the recommended medication. It was preferable for patients to simply include oily fish as part of a healthy diet. I guess if you take capsules your body will use what it needs and get rid of the rest.
Was there any indicator that a heart attack was likely or a risk?A lot of the research on cod liver oil isn't actually that good when it comes to long term stuff, most of it is within 1-2 years. There's also the issue that if someone has a lot of free radicals in their blood (eg due to oxidative stress > dysfuncitonal mitochondria) those free radicals can very easily alter the unsaturated fats of EPA/DHA and can become harmful. I am a fan of supplements, but I'm a fan of a healthy diet first. I think there are supplements a huge number of us should be taking or could benefit from, but considering how easy it is to get omega 3 in the diet, I don't think it is necessary.
Sticks. said:
The cod liver oil I take contains vit A and D. Excessive intake of vit D can cause problems with calcium build up apparently.
It can, but you need to go mad, like, really mad, unless you have issues with your parathyroids. Plus, I can guarantee the dose in a "multi" will be crap. 3-5000iu/day is a lovely healthy amount (unless obese, need more). Ideally supplement with vitamin K2 MK4 1000mcg/day and MK7 200mcg/day) to help direct calcium to the bones.I have loads of peer reviewed articles on this stuff (this is my speciality) and the risk of vitamin D toxicity is incredibly low. Put it this way, in some kids with rickets or adults with osteomalacia they'll give them "hammer doses" of 300,000iu in one hit.
ReverendCounter said:
bigpriest said:
Interesting, because after a heart attack 10 years ago, amongst the recommended daily medication to reduce the risk of another attack was Fish Oil capsules. However, a clinical decision was made some years later that there was not enough evidence to support the claims, therefore Fish Oil was removed from the recommended medication. It was preferable for patients to simply include oily fish as part of a healthy diet. I guess if you take capsules your body will use what it needs and get rid of the rest.
Was there any indicator that a heart attack was likely or a risk?This is from MIMS:
Omega-3 fatty acids can no longer be prescribed to prevent further cardiovascular events in patients who have had a myocardial infarction, after an EMA review concluded they are ineffective in this setting.
The EMA reviewed all the available evidence and concluded that the small relative-risk reduction seen in the original 1999 open-label study of omega-3 supplements in secondary prevention, which supported the initial authorisation of these medicines, was not confirmed in more recent randomised controlled trials.
This indication is therefore being removed from the prescribing information for the two omega 3-fatty acid medicines currently available, Teromeg and Omacor. Both are 1g capsules containing ethyl esters of the fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
Earlier this year a randomised, placebo-controlled trial in 25,000 people failed to show any protective effect of omega-3 supplements against cardiovascular disease or cancer.
Omega-3 fatty acids can still be prescribed for the treatment of hypertriglyceridaemia when dietary measures alone are insufficient.
bigpriest said:
No symptoms at all, age wasn't a factor (41), general health was good. Family history would have flagged as a potential risk if known at the time.
Thanks for following up, the heart attack must have been a real shock given the lack of indicators.Can I just try to clarify as I'm not sure - but the comments "Earlier this year a randomised, placebo-controlled trial in 25,000 people failed to show any protective effect of omega-3 supplements against cardiovascular disease or cancer" - these results aren't generated from 25,000 people who have already had a myocardial infarction as per the previous MIMS EMA decision and comments?
That these 25k were randomised from a group who had not suffered heart health related issues?
TyrannosauRoss Lex said:
There's also the issue that if someone has a lot of free radicals in their blood (eg due to oxidative stress > dysfuncitonal mitochondria) those free radicals can very easily alter the unsaturated fats of EPA/DHA and can become harmful.
Does this mean that being in a state of ketosis is more likely to enable this alternation? I was once told that being in ketosis puts your cells in a state of oxidative stress?ReverendCounter said:
TyrannosauRoss Lex said:
There's also the issue that if someone has a lot of free radicals in their blood (eg due to oxidative stress > dysfuncitonal mitochondria) those free radicals can very easily alter the unsaturated fats of EPA/DHA and can become harmful.
Does this mean that being in a state of ketosis is more likely to enable this alternation? I was once told that being in ketosis puts your cells in a state of oxidative stress?I'm not generally a fan of "diets" per se, but more a diet that is "nutrient dense" (ie lots of nutritional value for the intake of calories). Lots of fresh fruit and veg, cut back on the crap. I eat a whole foods diet and have no artificial or man-made stuff in my diet. No chocolate, cakes, biscuits etc. I tend to get between 10-15 portions of fruit and veg per day(!!!!). I do supplement with a number of things though which are often very hard to get "optimum" levels via diet: active B12 (methylcobalamin) and a methylation support supplement (I use Seeking Health's Homocystex Plus), 10g/day glycine, vitamin D 4000iu/day, magnesium citrate, potassium citrate, vitamin K2 (MK4 and MK7) and, because I do a lot of sport, collagen powder and glutamine and finally....for my immune system.....liposomal glutathione.
It's an awful lot of supplements but I only take what the research has proven to be beneficial. I used to take fish oil but I don't any more, the research isn't good enough for me. In reality it's most likely overboard, but I can do 12 hour days at work and not feel tired, and I just feel very healthy
Sorry for the lengthy post.
Gassing Station | Health Matters | Top of Page | What's New | My Stuff