Discussion
Question
Could you please give me some information on the antibiotic Metronidazole and why it is not advisable to drink alcohol when taking this drug?
Answer
Metronidazole is believed to have the ability to block the body's breakdown of alcohol, leading to an accumulation of a substance called acetaldehyde in the bloodstream.
Theoretically, this may occur within 10 minutes of ingestion of alcohol and may last several hours.
It is said to be characterised by intense flushing, breathlessness, headache, increased or irregular heart rate, low blood pressure, nausea and vomiting.
This possible reaction is dangerous because it is so unpredictable and may be extremely severe.
A review of the literature between 1969 and 1982 reports cases involving eight patients, four of which were serious, including one death.
Although there has been little in the way of published pharmacological evidence to support this interaction with alcohol.
So in summary, although the reported risk is thought to be extremely small and perhaps not very well established in fact, caution should be exercised both with traditional alcoholic beverages and spirits.
Seems like you'll be ok after all.
Could you please give me some information on the antibiotic Metronidazole and why it is not advisable to drink alcohol when taking this drug?
Answer
Metronidazole is believed to have the ability to block the body's breakdown of alcohol, leading to an accumulation of a substance called acetaldehyde in the bloodstream.
Theoretically, this may occur within 10 minutes of ingestion of alcohol and may last several hours.
It is said to be characterised by intense flushing, breathlessness, headache, increased or irregular heart rate, low blood pressure, nausea and vomiting.
This possible reaction is dangerous because it is so unpredictable and may be extremely severe.
A review of the literature between 1969 and 1982 reports cases involving eight patients, four of which were serious, including one death.
Although there has been little in the way of published pharmacological evidence to support this interaction with alcohol.
So in summary, although the reported risk is thought to be extremely small and perhaps not very well established in fact, caution should be exercised both with traditional alcoholic beverages and spirits.
Seems like you'll be ok after all.
James P said:
ali_kat said:
Can you not start taking them Sunday?
I suspect that RWR will not allow halves to be consumed - a pint of coke about every 5 minutes is not very appealing
Buggeration.
Anyway it is an improvement, I was concerned I might not be able to come at all.
V8mate said:
Question
Could you please give me some information on the antibiotic Metronidazole and why it is not advisable to drink alcohol when taking this drug?
Answer
Metronidazole is believed to have the ability to block the body's breakdown of alcohol, leading to an accumulation of a substance called acetaldehyde in the bloodstream.
Theoretically, this may occur within 10 minutes of ingestion of alcohol and may last several hours.
It is said to be characterised by intense flushing, breathlessness, headache, increased or irregular heart rate, low blood pressure, nausea and vomiting.
This possible reaction is dangerous because it is so unpredictable and may be extremely severe.
A review of the literature between 1969 and 1982 reports cases involving eight patients, four of which were serious, including one death.
Although there has been little in the way of published pharmacological evidence to support this interaction with alcohol.
So in summary, although the reported risk is thought to be extremely small and perhaps not very well established in fact, caution should be exercised both with traditional alcoholic beverages and spirits.
Seems like you'll be ok after all.
So he only might die? Could you please give me some information on the antibiotic Metronidazole and why it is not advisable to drink alcohol when taking this drug?
Answer
Metronidazole is believed to have the ability to block the body's breakdown of alcohol, leading to an accumulation of a substance called acetaldehyde in the bloodstream.
Theoretically, this may occur within 10 minutes of ingestion of alcohol and may last several hours.
It is said to be characterised by intense flushing, breathlessness, headache, increased or irregular heart rate, low blood pressure, nausea and vomiting.
This possible reaction is dangerous because it is so unpredictable and may be extremely severe.
A review of the literature between 1969 and 1982 reports cases involving eight patients, four of which were serious, including one death.
Although there has been little in the way of published pharmacological evidence to support this interaction with alcohol.
So in summary, although the reported risk is thought to be extremely small and perhaps not very well established in fact, caution should be exercised both with traditional alcoholic beverages and spirits.
Seems like you'll be ok after all.
Is there some kind of sweepstake we could hold on this?
James P said:
ali_kat said:
Can you not start taking them Sunday?
Just pretend the buses were on strike and you couldn't get to your hospital appointment until Sunday.
Good get out clause though I'll give you that... you do realise that there are no Le Mans medical cars to have a go in at BTaP?
markmullen said:
Pints of coke will be no trouble.
We can get you some alcohol free lager & wine too for variety 
markmullen said:
Buggeration.
Sounds like Kinky's EFA on the other thread might be true 
markmullen said:
Anyway it is an improvement, I was concerned I might not be able to come at all.
Tis very good newsI'm assuming 'cause you got them from hospital that you can't just not start to take them until Sunday
How about stop taking them Saturday breakfast & start again Sunday breakfast? Would that work?Consult your Dr - mine is usually pretty understanding and will advise me of 'work arounds'
The Unfailing Fountain Of Truth AKA Wikipedia said:
Consuming ethanol (alcohol) while using metronidazole has long been thought to have a disulfiram-like reaction with effects that can include nausea, vomiting, flushing of the skin, tachycardia (accelerated heart rate), and shortness of breath, however there are studies calling that notion into question. Consumption of alcohol should be avoided by patients during systemic metronidazole therapy and for at least 48 hours after completion of treatment. However, the mechanism of this reaction in the clinical setting has recently been questioned by some authors, and a possible central toxic serotonin reaction for the alcohol intolerance suggested.
There you are, you see. It's just a central toxic serotonin reaction!Which doesn't sound the least bit worrying, oh no sir.
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